Effects of Yoga on Cognitive and Immune Function in Colorectal Cancer

University of Michigan

Status: Completed

Conditions: Colorectal Neoplasms

Treatments: Other: Yoga; Other: Physical Activity

Study type: Interventional

Funder types: Other

Identifiers

NCT02564835

HUM00096913

Details and patient eligibility

About

The purpose of this study is to determine if individuals with colorectal cancer enjoy yoga and to begin to assess whether yoga is effective in improving attention and immune function in individuals with colorectal cancer compared to physical activity and usual care.

Full description

The proposed study will use a prospective RCT pilot design with three arms (yoga, resistance and flexibility exercise, usual care) and a total of 60 men and women who have completed therapy (> 6 months post primary or adjuvant therapy) to accomplish the specific aims. Equal numbers of men and women will be randomized into each arm of the study. Participants will be tested before, immediately after, and 3-months after treatment or similar time points for the usual care group. After data has been collected, participants who were randomized to the resistance and flexibility exercise group (active control group) or to the usual care group will be provided with the opportunity to participate in the yoga intervention.

Enrollment: 27 patients

Sex: All

Ages: 21+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• a history of any stage new or recuurent colorectal cancer
• great then 6 months post treatment for colorectal cancer
• report not fully recovered from the effects of cancer and cancer treatment
• no clinical signs or symptoms of brain metastasis
• normal (or corrected to normal) hearing and vision
• able to read and write English

Exclusion criteria

• conditions that could affect participation in yoga such as spinal disease or unstable joints

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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27 participants in 3 patient groups

Yoga

Experimental group

Description:

The Yoga Program includes two 90-minute classes every week tor a total of 12 weeks.

Treatment:

Other: Yoga

Physical Activity

Active Comparator group

Description:

The Physical Activity Program includes two 90-minutes classes every week for a total of 12 weeks.The intervention is based on the Exercise for People Living with Cancer program and will include nine resistance exercises (e.g. standing push up, squats, standing leg curl) and 8 flexibility exercises (e.g. shoulder stretch, quadriceps stretch, hamstrings and lower back stretch) targeted for the whole body as well as a brief warm up and cool down (walking).

Treatment:

Other: Physical Activity

Usual Care

No Intervention group

Description:

Participants randomized to this arm will receive standard care only.