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Effects of Yoga on Sodium-induced Pressor Responses in African American Adults

T

Texas State University

Status

Completed

Conditions

Blood Pressure

Treatments

Behavioral: Yoga
Behavioral: Waitlist control

Study type

Interventional

Funder types

Other

Identifiers

Details and patient eligibility

About

This investigation aims to determine the effects of a 4-week yoga intervention on sodium-induced pressor and endothelial function responses as well as markers of renal sodium handling in African American adults.

Enrollment

15 patients

Sex

All

Ages

18 to 60 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • African American
  • Adults ages 18-60 years

Exclusion criteria

  • pregnancy or within 60 days postpartum
  • having taken blood pressure (including diuretics beta-blockers, ACE inhibitors, angiotensin receptor blockers, and calcium channel blockers) or statin medications within the past 3 months (statins have been demonstrated to reduce oxidative stress which could impact flow-mediated dilation);
  • infection (viral or other) within the past 4 weeks;
  • having adrenal or endocrine tumors (these could impact BP);
  • renal disease defined as a glomerular filtration rate (GFR) of less than 60 (creatinine will be tested at initial screening and GFR will be calculated);
  • prior myocardial infarction; vii) known coronary heart disease;
  • personal history of stroke;
  • heart failure;
  • cardiac arrhythmias;
  • chronic obstructive pulmonary disease;
  • recent chest pain or dyspnea;
  • orthopedic limitations that preclude the execution of yoga postures;
  • current insulin dependence;
  • currently taking steroid medications;
  • currently undergoing chemotherapy or radiation;
  • having practiced yoga or yogic breathing techniques at least once weekly consistently within the past 3 months;
  • heat intolerance or electrolyte imbalances (hypo- or hyper-natremia or hypo- or hyper-kalemia).

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

None (Open label)

15 participants in 2 patient groups

Yoga
Experimental group
Description:
Yoga sessions (35 minutes each) will be performed 5 times weekly for 4 weeks.
Treatment:
Behavioral: Yoga
Waitlist control
Other group
Description:
Waitlisted participants will maintain their normal diet and exercise patterns for 4 weeks prior to rerandomization to the yoga group.
Treatment:
Behavioral: Waitlist control

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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