Effects on Glucose Homeostasis of Changes in Plasma Lipoproteins Induced by Nutritional and Pharmacologic Strategies

Azienda Ospedaliero, Universitaria Pisana

Status: Invitation-only

Conditions: Glucose Metabolism Disorders

Treatments: Dietary Supplement: Intermittent Fasting; Dietary Supplement: Low-Carbohydrate/High-Protein diet; Drug: Fibrates

Study type: Interventional

Funder types: Other

Identifiers

NCT05213988

GLUCO-STAR

Details and patient eligibility

About

The investigators aim to examine the impact of changes in plasma lipoproteins induced by nutritional and pharmacological interventions on glucose homeostasis

Enrollment: 50 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age 18-65 years
• both males and females

Exclusion criteria

• acute or chronic conditions influencing glucose and lipid metabolism
• pregnancy

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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50 participants in 4 patient groups

Low-Carbohydrate/High-Protein Diet

Experimental group

Treatment:

Dietary Supplement: Low-Carbohydrate/High-Protein diet

Fibrate

Experimental group

Treatment:

Drug: Fibrates

Intermittent Fasting

Experimental group

Treatment:

Dietary Supplement: Intermittent Fasting

Control

No Intervention group