Effects on Glutamine on the Outcome of Allogeneic Bone Marrow Transplant Recipients

Hospital Authority, Hong Kong

Status: Unknown

Conditions: Pulmonary Veno-Occlusive Disease; Mucositis; Hepatic Veno-Occlusive Disease

Treatments: Drug: Glutamine

Study type: Interventional

Funder types: Other

Identifiers

NCT00563498

HARECCTR0500034

EC1432-00

Details and patient eligibility

About

The primary purpose of this project is to investigate if addition of glutamine, an amino acid, to standard parenteral nutrition, may improve the clinical outcome of the bone marrrow transplantation reducing the occurrence of veno-occlusive disease and severity of mucositis.

Enrollment: 40 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Allogeneic bone marrow transplant recipients using busulfan and cyclophosphamide as conditioning.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind