Effects on the Diagnostic Accuracy of Magnetic Imaging Angiographies of the Supra-Aortic Vessels by Three Different Magnetic Resonance Contrast Agents in Patients

University Hospital Muenster

Status and phase: Unknown; Phase 4

Conditions: Epilepsy; Dizziness; Headache

Treatments: Drug: Contrast agent

Study type: Interventional

Funder types: Other

Identifiers

NCT00132223

0710/2004-IKR

Details and patient eligibility

About

Angiographies of the supra-aortic vessels by magnetic imaging have become common recently. So it was the purpose of this study to evaluate the imaging potential of different contrast agents.

Three contrast agents for magnetic resonance imaging are compared in angiographies of the supra-aortic arteries in a intraindividual study of 10 patients.

All applications of these contrast agents are performed with a flow of 2 ml/s. One contrast medium is applicated a second time with a reduced flow of 1 ml/s.

The angiographies of the supra-aortic vessels are evaluated by two experienced readers in a consensus reading. The signal/noise- and contrast/noise-ratio of anatomic vessel segments of the carotic and vertebral arteries are measured and compared to each other.

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Headache
• Epilepsia
• Dizziness

Exclusion criteria

• Pregnancy
• Metal implants (e.g. pacemaker)
• Contraindication for contrast agent
• Multiple allergies

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: Single Blind