Effects Oxygen Supplementation Determined Better Exercise Capacity in Eisenmenger Syndrome

Federal University of São Paulo

Status: Completed

Conditions: Hypertension, Pulmonary; Eisenmenger Complex

Treatments: Other: Oxygen Supplementation

Study type: Interventional

Funder types: Other

Identifiers

NCT02661802

13473813.1.0000.5505

Details and patient eligibility

About

The purpose of this study was to evaluate the acute effects of oxygen supplementation during a submaximal exercise test in patients with Eisenmenger's Syndrome.

Full description

Patients with Eisenmenger's syndrome were submitted to a submaximal exercise test (six-minute walking test) with and without supplemental oxygen. The distance walked during the two tests were compared to assess the impact of oxygen supplementation on the walking distance.

Enrollment: 30 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Abscence of heart failure and/or respiratory infection
• Advanced therapy for pulmonary hypertension

Exclusion criteria

• Lung, liver or connective tissue diseases
• Neuromuscular diseases
• Inability to perform a pulmonary function test and/or chronic lung disease
• Inability to walk

Trial design

Primary purpose: Supportive Care

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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30 participants in 1 patient group

Oxygen Supplementation

Experimental group

Description:

Two six-minute walk tests, one with oxygen supplementation and another without were performed on different days. During the test with oxygen supplementation the delivery was continuous by mask at 40% and technician walked behind the patient with the oxygen source.

Treatment:

Other: Oxygen Supplementation