Efficacy and Safety Assessment of Niacinamide Cosmetic Preparation: a Randomized Controlled Trial

University of Split

Status: Enrolling

Conditions: Skin Hyperpigmentation; Dry Skin; Eczema

Treatments: Other: No treatment (usual skincare rutine); Other: miss alice face it you love me serum

Study type: Interventional

Funder types: Other

Identifiers

NCT06189105

2181-198-03-04-23-032

Details and patient eligibility

About

Niacinamide in lower concentrations has been recognized as a cosmetic ingredient with hydrating properties. Therefore, aim was to test the efficacy and safety of niacinamide cosmetic preparation in A Randomized, Controlled Trial.

Full description

Skin hydration (as use of hydrating cosmetic ingredients) is one of the most interventions for healthy skin and skin barrier function. Therefore, cosmetic ingredients used for this purpose should be examined for their efficacy.

Enrollment: 25 estimated patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy volunteers who gave written informed consent

Exclusion criteria

• skin disease, skin damage on measurement sites, use of corticosteroids and immunomodulators a month prior to the inclusion and during the trial, non-adherence to the trial protocol, exposure to artificial UV radiation, pregnancy and lactation

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Triple Blind

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25 participants in 2 patient groups, including a placebo group

experimental arm

Experimental group

Description:

Use of facial serum with niacinamide, plant-based collagen and peptides on randomized site on forehead

Treatment:

Other: miss alice face it you love me serum

placebo comparator

Placebo Comparator group

Description:

No treatment (usual skincare rutine)

Treatment:

Other: No treatment (usual skincare rutine)