ClinicalTrials.Veeva

Menu

Efficacy and Safety of Cold Versus Hot Snare Polypectomy for Removal of 4-10 mm Pedunculated Colorectal Polyps

S

Shandong University

Status

Not yet enrolling

Conditions

Colorectal Polyps

Treatments

Procedure: hot snare polypectomy
Procedure: cold snare polypectomy

Study type

Interventional

Funder types

Other

Identifiers

Details and patient eligibility

About

This was a non-inferiority randomized controlled trial designed to compare the efficacy and safety of cold versus hot snare polypectomy for the removal of 4-10 mm pedunculated colorectal polyps. The primary outcome was delayed postpolypectomy bleeding. The secondary outcomes included immediate postpolypectomy bleeding, procedure time, en bloc resection, complete histologic resection, use of haemostatic clips and perforation rate.

Enrollment

196 estimated patients

Sex

All

Ages

18 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  1. 18-80 years old, male and female
  2. Proposed colonoscopy and colonoscopy detection of at least one 4-10 mm pedunculated colorectal polyp

Exclusion criteria

  1. Contraindication to colonoscopy or polypectomy
  2. Use of antiplatelet or anticoagulant drugs within 1 week before polypectomy
  3. Alarming signs and symptoms of colorectal cancer (blood in stool, black stool, unexplained anaemia and weight loss, abdominal mass, positive rectal examination; or imaging and laboratory tests highly suspicious for colorectal cancer) or endoscopic manifestations of polyps highly suspicious for high-grade intraepithelial neoplasia or carcinoma
  4. Comorbidity with inflammatory bowel disease, colonic polyposis, or active gastrointestinal bleeding
  5. Inadequate bowel preparation
  6. Pregnant or lactating women
  7. Failure to sign the informed consent form
  8. Patients deemed ineligible by investigators to enrol in the trial

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

196 participants in 2 patient groups

cold snare polypectomy group
Experimental group
Treatment:
Procedure: cold snare polypectomy
hot snare polypectomy group
Active Comparator group
Treatment:
Procedure: hot snare polypectomy

Trial contacts and locations

1

Loading...

Central trial contact

Yanqing Li

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2025 Veeva Systems