Efficacy and Safety of Erector Spinal Plane Block (ESPB) for Analgesia in Laparoscopic Cholecystectomy

Beijing Tsinghua Chang Gung Hospital

Status: Unknown

Conditions: Analgesia

Treatments: Procedure: Erector spinal plane block

Study type: Interventional

Funder types: Other

Identifiers

NCT04648345

20004-0-01

Details and patient eligibility

About

Purpose: to evaluate the efficacy and safety of erector spinal block (ESB) for analgesia in laparoscopic cholecystectomy（LC）.

Method: This study is a randomized, single-blind, controlled clinical trial. Pre-operative ultrasound-guided bilateral erector spinae plane block will be performed in the ESPB group. Vertebral side block will be performed in the VSB group. And the control group will receive local anaesthesia after the surgery. Intraoperative and postoperative analgesia effect and side effects will be compared between the three groups.

Enrollment: 90 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• American Society of Anesthesiologists (ASA) physical status 1-3
• Scheduled for elective laparoscopic cholecystectomy surgery under general anesthesia

Exclusion criteria

• patient refusal
• pregnancy
• history of allergy to study drugs
• neurological and cognitive disorders
• coagulopathy
• chronic pain disorders
• infections at the injection site
• history of abdominal surgery

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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90 participants in 3 patient groups, including a placebo group

Erector spinal plane block group (ESPB group)

Experimental group

Description:

After induction of general anesthesia, pre-operative ultrasound-guided bilateral erector spinae plane block will be performed in the ESPB group.

Treatment:

Procedure: Erector spinal plane block

Vertebral side block group (VSB group)

Active Comparator group

Description:

After induction of general anesthesia, pre-operative ultrasound-guided bilateral vertebral side block will be performed in the VSB group.

Treatment:

Procedure: Erector spinal plane block

Local block group （LB group）

Placebo Comparator group

Description:

Local block will be performed at the surgical incisions after the surgery under general anesthesia.

Treatment:

Procedure: Erector spinal plane block