Efficacy and Safety of Etrasimod in Elderly Patients With Ulcerative Colitis

Showa Inan General Hospital

Status: Enrolling

Conditions: Ulcerative Colitis (Disorder)

Treatments: Drug: Etrasimod administration

Study type: Interventional

Funder types: Other

Identifiers

NCT07243639

Etrasimod in elderly UC

Details and patient eligibility

About

Eligible patients will be identified in regular clinical practice. After providing thorough explanation and obtaining voluntary written informed consent, the clinical course, adverse events, endoscopic findings, and histopathological changes in biopsy specimens after Etrasimod administration will be prospectively collected and analyzed.

Enrollment: 30 estimated patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with active ulcerative colitis

Exclusion criteria

• the presence of acute or chronic renal failure, chronic heart disease, pulmonary infection, liver cirrhosis, colorectal cancer, autoimmune disease, and infectious disease

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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30 participants in 1 patient group

elderly patients (aged 65 years or older) with active ulcerative colitis

Experimental group

Treatment:

Drug: Etrasimod administration