Efficacy and Safety of Extract of Gelidium Elegans

Yonsei University

Status: Completed

Conditions: Obesity

Treatments: Dietary Supplement: Placebo; Dietary Supplement: Exract of Gelidium elegans

Study type: Interventional

Funder types: Other

Identifiers

NCT03842774

4-2017-0860

Details and patient eligibility

About

Extract of Gelidium elegans inhibits lipid differentiation, accumulation, and synthesis in vitro and in vivo. It has also anti-obesity effect by inhibiting weight gain and decreasing body fat. In a preliminary study of obese adults aged 20 years or older, the extracts of Gelidium elegans showed a tendency to decrease in body fat and visceral fat, and to increase lean body mass. Based on these results, we tried to confirm the effect of body weight and body fat reduction of Gelidium elegans extract in overweight and obese people.

Enrollment: 94 patients

Sex: All

Ages: 19 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 1. Between the ages of 19 and 50
• 2. BMI is at or greater than 23 and less than 30 kg/m^2

Exclusion criteria

• 1. uncontrolled hypertension
• 2. uncontrolled diabetes
• 3. current serious cerebrovascular and cardiovascular disease

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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94 participants in 2 patient groups, including a placebo group

Test group

Experimental group

Description:

taken 3 tablets of Gelidium elegans extract (1000 mg/day) once a day for 12 weeks

Treatment:

Dietary Supplement: Exract of Gelidium elegans

Control group

Placebo Comparator group

Description:

taken 3 tablets of placebo once a day for 12 weeks

Treatment:

Dietary Supplement: Placebo