Efficacy and Safety of Fermented Ginseng Powder on Liver Function

Chonbuk National University

Status: Completed

Conditions: Fatty Liver, Nonalcoholic

Treatments: Dietary Supplement: fermented ginseng powder; Dietary Supplement: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT03260543

GB-LFE-GP

Details and patient eligibility

About

This study was conducted to investigate the effects of daily supplementation of fermented ginseng powder on improvement of Liver function.

Full description

The investigators performed a 12-week, randomized, double-blind, placebo-controlled human trial to evaluate the efficacy and safety of fermented ginseng powder on improvement of Liver function. The investigators measured ALT(Alanine Transaminase) profiles, Liver function index, fatty liver grade, lipid metabolism index, total antioxidant capacity, imflammation index, and Multidimensional Fatigue Scale.

Enrollment: 90 patients

Sex: All

Ages: 19 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age 19-70 years with ALT 35-105 IU/L

Exclusion criteria

• Under antipsychotic drugs therapy within past 2 months

• History of alcohol or substance abuse

• Participation in any other clinical trials within past 2 months

• Laboratory test by show the following results

  • Serum Creatinine > 2.0 mg/dl

• Pregnancy or breast feeding etc.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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90 participants in 2 patient groups, including a placebo group

fermented ginseng powder

Experimental group

Description:

tablets (2 tablets/day, 125 mg \& 500 mg/day) for 12 weeks.

Treatment:

Dietary Supplement: fermented ginseng powder

Placebo

Placebo Comparator group

Description:

Placebo for 12 weeks.

Treatment:

Dietary Supplement: Placebo