Efficacy and Safety of Gynostemma Pentaphyllum(Dungkulcha) Extract on Alleviation of Chronic Stress-induced Strain

Chonbuk National University

Status

Completed

Conditions

Chronic Stress-Induced Strain

Treatments

Dietary Supplement: Placebo

Dietary Supplement: Gynostemma Pentaphyllum(Dungkulcha) Extract(400mg/day)

Study type

Interventional

Funder types

Other

Identifiers

NCT03277833

CBU-STR-DOLWOE

Details and patient eligibility

About

The investigators performed a 8-week, randomized, double-blind, placebo-controlled human trial to evaluate the efficacy and safety of Gynostemma Pentaphyllum(Dungkulcha) on alleviation of chronic stress-induced strain. The investigators measured decrement of body fat parameters, State&Trait version of STAI, Beck Anxiety Inventory(BAI), Hamilton Anxiety Inventory(HAM-A), and monitored their blood pressure.

Enrollment

72 patients

Sex

All

Ages

20 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

• Age 20-65 years with chronic stress( S-STAI score 40~60)

Exclusion criteria

excessive physically chronic fatigue
Subjects taking antidepressants, anxiolytics, hypnotics within the last 2 months prior to the study
Cardiovascular disease
Allergic or hypersensitive to any of the ingredients in the test products
History of reaction to any of the test products or of gastrointestinal diseases such as Crohn's disease or gastrointestinal surgery
Participation in any other clinical trials within past 2 months
Renal disease
Abnormal hepatic function
Laboratory test, medical or psychological conditions deemed by the investigators to interfere with successful participation in the study
History of alcohol or substance abuse
Pregnancy or lacting women etc.