Efficacy and Safety of Ivabradine to Reduce Heart Rate Prior to Coronary CT-angiography in Advanced Heart Failure: Comparison With β-Blocker

Rajaie Cardiovascular Medical and Research Center

Status: Unknown

Conditions: Heart Rate Low; Heart Failure, Diastolic; Heart Failure, Systolic; CT Angiography; Heart Failure; Non-ischemic Cardiomyopathy; Heart Failure，Congestive; Ischemic Cardiomyopathy

Treatments: Drug: Ivabradine; Drug: Metoprolol

Study type: Interventional

Funder types: Other

Identifiers

NCT03830957

HFRC_01

Details and patient eligibility

About

The aim of this study is to compare the effects of Ivabradine and metoprolol to reduce heart rate prior to coronary CT angiography in patients with advanced heart failure.

Enrollment: 200 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Sinus rhythm
• Heart rate >60/min

Exclusion criteria

• Atrial fibrillation
• Any contraindication for beta-blocker use

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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200 participants in 2 patient groups

Ivabradine

Active Comparator group

Treatment:

Drug: Ivabradine

metoprolol

Active Comparator group

Treatment:

Drug: Metoprolol