Efficacy and Safety of Salmon Calcitonin Nasal Spray in Improving Muscle Strength and Reducing Pain After Forearm Fracture in Postmenopausal Women

Novartis

Status and phase

Completed

Phase 4

Conditions

Forearm Fracture

Treatments

Drug: Salmon calcitonin

Study type

Interventional

Funder types

Industry

Identifiers

NCT00239889

CSMC051A2402

Details and patient eligibility

About

Calcitonin has been used for many years for treating osteoporosis in postmenopausal women, and it has been shown that calcitonin reduces pain after spine and hip fracture in women with osteoporosis. Therefore, this study assesses the safety and efficacy of salmon calcitonin nasal spray on muscle strength after a forearm fracture, pain, quality of life and fracture healing in postmenopausal women.

Sex

Female

Ages

60+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Post-menopausal women, aged at least 60 years old
Having a forearm fracture within the last 3-7 days before treatment
Fracture is treated with either a plaster cast only, or a cast plus Kirschner wires

Exclusion criteria

Multiple fractures, severe fractures, or the forearm fractured in more than one place
Nerve damage in the forearm caused by the fracture
Other conditions which would interfere with the grip strength measurements (e.g. swelling, paralysis, skin diseases or rheumatoid arthritis)

Other protocol-defined inclusion/exclusion criteria may apply.