Efficacy and Safety on the Use of Bisphosphonates in Paediatrics

Centre Hospitalier Universitaire de Nīmes

Status: Completed

Conditions: Bisphosphonate-Associated Osteonecrosis; Bone Fragile; Adverse Events; Children

Treatments: Other: No intervention, observational study

Study type: Observational

Funder types: Other

Identifiers

NCT04012320

Local/2018/TAT-01

Details and patient eligibility

About

The investigators suppose that the impact of bisphosphonate therapy is beneficial on the bone during the growth period with few adverse events.

Enrollment: 99 patients

Sex: All

Ages: Under 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• be under 18 years of age
• have been treated by intravenous bisphosphonates for primary or secondary osteoporosis

Exclusion criteria

• be over 18 years of age

Trial design

99 participants in 2 patient groups

Pamidronate therapy

Treatment:

Other: No intervention, observational study

Zoledronate therapy

Treatment:

Other: No intervention, observational study