Efficacy And Safety Study Of Atorvastatin Versus Simvastatin In Type 2 Diabetic Subjects With Hypercholesterolemia

Viatris

Status and phase: Completed; Phase 4

Conditions: Hypercholesterolemia

Treatments: Drug: Simvastatin; Drug: Atorvastatin

Study type: Interventional

Funder types: Industry

Identifiers

NCT00141141

A2581053

Details and patient eligibility

About

The purpose of this study is to evaluate the efficacy of Atorvastin vs Simvastatin in decreasing LDL-C in diabetic subjects with hypercholesterolemia at the end of the treatment phase.

Enrollment: 383 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis of type 2 diabetes mellitus
• LDL-C > 130 mg/dL

Exclusion criteria

• Insulin therapy
• Clinically relevant organ disease (creatininemia >2mg/dL, CHF NYHA III and IV)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)