Efficacy and Safety Study of Catheter Ablation for Atrial Fibrillation

Wuhan University

Status and phase: Unknown; Phase 4

Conditions: Atrial Fibrillation

Treatments: Procedure: catheter ablation

Study type: Interventional

Funder types: Other

Identifiers

NCT01113294

AFCT001

Details and patient eligibility

About

To compare the efficacy of different procedures, identify the optimal procedure, ablation sites, ablation endpoints and post-operative anticoagulation strategy, establish the optimal treatment strategy for atrial fibrillation.

Enrollment: 2,040 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Atrial fibrillation recorded by ECG or Holter;
2. Age: 18 ~ 75 years;
3. Patients who are willing to enroll in the trial

Exclusion criteria

1. Patients accompanied hyperthyroidism;
2. Patients with sever liver or renal dysfunction;
3. Patients with sever cardiac dysfunction;
4. Patients had previous radiofrequency catheter ablation in the LA or Maze surgical procedure;
5. Patients with emboli in atrium;
6. Pregnant woman

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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2,040 participants in 1 patient group

ablation

Experimental group

Treatment:

Procedure: catheter ablation