Efficacy and Saffety of Oral Immunotherapy to Pistachio

Central Hospital, Nancy, France

Status: Completed

Conditions: Food Allergy; Allergy

Treatments: Other: Food allergy

Study type: Observational

Funder types: Other

Identifiers

NCT05698030

2022PI182

Details and patient eligibility

About

The objectives of this study are (i) to evaluate the efficacy of oral immunotherapy to pistachio by evaluating the daily oral tolerance of 2g pistachio, by evaluating the long-term tolerance of 15g pistachio (sustained unresponsiveness) and by decreasing pistachio-specific IgE, (ii) evaluating the efficacy of pistachio immunotherapy on cashew tolerance, (iii) and to evaluate the safety of pistachio immunotherapy.

Enrollment: 50 patients

Sex: All

Ages: 1 to 18 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients under 18 years of age with a proven allergy to pistachio and followed in the pediatric allergology unit of the Nancy University Hospital.
• Patients who have received oral immunotherapy to pistachio for at least 18 months at 31/12/2022

Exclusion criteria

• Patients who have received oral immunotherapy to pistachio for less than 18 months.
• Patients lost to follow-up for more than 2 years or last consultation dating from 2020 or earlier