Efficacy at One Year of Combined Injections of Plasma Rich in Platelets and Hyaluronic Acid in Knee Osteoarthritis (ISPAG)

Centre Hospitalier Universitaire, Amiens

Status: Enrolling

Conditions: Platelet Rich Plasma; Hyaluronic Acid; Knee Osteoarthritis

Study type: Observational

Funder types: Other

Identifiers

NCT05039463

PI2021_843_0178

Details and patient eligibility

About

The French Society of Rheumatology cannot rule on the value of intra-articular injections of PRP due to the lack of hindsight and insufficient data. In fact, the injection protocols are very heterogeneous in terms of preparation method, the presence or not of leukocytes, the number of centrifugations, the volume injected, the ultrasound guidance, which makes it difficult to analyze the literature. The investigator objective is therefore to evaluate the effectiveness of combined injections of PRP and hyaluronic acid.

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age : > 18 years old
• Patients benefiting, in the context of knee osteoarthritis, from viscosupplementation alone or from two injections of PRP, in combination with HA, at the Amiens University Hospital.

Exclusion criteria

• Patient refusal to use the data
• Language barrier
• Age less than 18 years old.

Trial design

100 participants in 2 patient groups

PRP + HA

Description:

two injections of PRP (plasma rich in platelets ), in combination with HA (hyaluronic acid)

HA alone

Description:

HA (hyaluronic acid)