Efficacy Evaluation of Products Against Long Wavelength Ultraviolet A1 and Visible Light Induced Biological Effects

Henry Ford Health

Status and phase: Active, not recruiting; Phase 2

Conditions: Sun Damaged Skin

Treatments: Drug: Sunscreening Agents

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT04181476

13223

Details and patient eligibility

About

The purpose of this study is to evaluate the efficacy of topical products in providing protection against the visible light and ultraviolet A1 (UVA1) part of sunlight. Ultraviolet radiation and visible light are both components of sunlight that reach the earth. It is important to test these topical products against visible light and UVA1 because our current sunscreens may not protect against these very well.

Enrollment: 12 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patient age 18 and older
• Patients Fitzpatrick skin phototype (SPT) III-IV with normal skin health
• Patient able to understand requirements of the study and risks involved

Exclusion criteria

• A recent history of vitiligo, melasma, and other disorders of pigmentation with the exception of post inflammatory hyperpigmentation
• A history of a relevant skin condition on any part of the patient's body (e.g. atopic dermatitis, eczema, vitiligo, sun burn, etc.
• A known history of photodermatoses
• A known history of photosensitivity disorders
• A known history of melanoma or non-melanoma skin cancers

Trial design

Primary purpose: Prevention

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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12 participants in 1 patient group

Topical products and Untreated areas

Other group

Description:

The subject will serve as their own control. Four different products will be tested.

Treatment:

Drug: Sunscreening Agents