Efficacy of a Brown Seaweed Extract Rich in Polyphenols on Glycemic Response to Sucrose in Human

innoVactiv

Status and phase: Completed; Phase 1

Conditions: Hyperglycemia

Treatments: Dietary Supplement: Reduction of glycemic index of ingested foods

Study type: Interventional

Funder types: Industry

Identifiers

NCT01384110

2010-RD-01-CLN

Details and patient eligibility

About

The primary endpoint of this trial will be to evaluate if a single administration in human of a lemon ice tea containing 500 mg of a polyphenol-rich algal powder is able to reduce postprandial glycemia and insulinemia.

Enrollment: 43 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy volunteer aged 18 to 60
• BMI between 20 and 30
• Non-smoking
• Using valid contraceptive method (women of childbearing age)

Exclusion criteria

• Iodine allergy, or allergy to components of the test product or placebo or standard meal
• Diabetes
• Use of dietary supplements for duration of study
• History of gastro-intestinal affections, anemia, major surgeries or surgeries of the stomach or digestive tract

Trial design

43 participants in 2 patient groups, including a placebo group

Brown Seaweed Lemon Tea

Experimental group

Description:

Single administration of lemon tea containing 500 mg of brown seaweed powder and 50 g of sucrose

Treatment:

Dietary Supplement: Reduction of glycemic index of ingested foods

Placebo lemon tea

Placebo Comparator group

Description:

Single administration of placebo lemon tea containing 50 g of sucrose

Treatment:

Dietary Supplement: Reduction of glycemic index of ingested foods