Efficacy of a Propolis-based Denture Cleanser

Raphael Freitas de Souza

Status: Completed

Conditions: Oral Candidiasis; Dental Plaque; Denture Stomatitis; Oral Hygiene

Treatments: Drug: Denture soaking solution; Drug: Saline solution

Study type: Interventional

Funder types: Other

Identifiers

NCT01237782

2009/53788-9 (Other Grant/Funding Number)

FORP-PT-002

2009.1.1081.58.6 (Other Identifier)

Details and patient eligibility

About

The purpose of this study is to assess if a propolis solution is able to remove plaque and kill microbes from complete dentures. The investigators will compare the results of the propolis-based denture cleanser with those obtained with an inactive solution.

Enrollment: 30 patients

Sex: All

Ages: 45+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Good general health
• Patients requesting new complete dentures
• Regular wearing of the same maxillary and mandibular complete dentures for at least one year
• Both denture bases and artificial teeth should be composed by acrylic resin

Exclusion criteria

• Unsatisfactory complete dentures in use (i.e. with poor fitting, relining or fractures)
• Pathologic changes in the oral cavity

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Quadruple Blind

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30 participants in 2 patient groups, including a placebo group

Propolis solution

Experimental group

Description:

A proprietary denture cleanser with propolis as the active agent.

Treatment:

Drug: Denture soaking solution

Saline solultion

Placebo Comparator group

Description:

Physiologic saline solution.

Treatment:

Drug: Saline solution