Efficacy of Acupuncture and Moxibustion Treatment in Patients With Active Crohn's Disease

Shanghai Institute of Acupuncture, Moxibustion and Meridian

Status

Completed

Conditions

CAM

Crohn's Disease

Treatments

Other: Control Group

Other: Treatment Group

Study type

Interventional

Funder types

Other

Identifiers

NCT01697761

SHACU-201202

Details and patient eligibility

About

The purpose of this study is to determine whether acupuncture or moxibustion therapies are effective in the treatment of active Crohn's disease. meanwhile, we are aim to observe the content of Inflammatory factors and Neurotransmitter before and after acupuncture and moxibustion therapy.

Full description

Through treating active Crohn's disease by acupuncture and moxibustion therapies for 12 weeks, we are aim to observe the efficiency and the probably change of Inflammatory factors and Neurotransmitter of colonic mucosa and we may elucidate the mechanism of the efficiency of acupuncture and moxibustion therapy.

Enrollment

92 patients

Sex

All

Ages

18 to 70 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

age 18-70 years;
Crohn's Disease Activity Index [CDAI]>150 and <450;
not taking any medication or taking salicylates, prednisone ( dose≤ 15mg and at least have taken a month ), after entering the study the dose remained constant;
Not taking immunosuppressive agents or use " with " biological preparations within 3 months prior to entering the study
signing a written informed consent form.

Exclusion criteria

Severe Crohn's disease patients or patients in remission ( CDAI > 450 or < 150 );
The pregnancy or lactation period patients ;
patients associated with heart, brain, liver, kidney and hematopoietic system disease;
The psychiatric patients;
Patients with other serious diseases.