Efficacy of Albendazole to Treat Intestinal Helminths and Its Effect on Gut Microflora

Albert Schweitzer Hospital

Status and phase: Completed; Phase 4

Conditions: Helminthiasis; Intestinal Diseases

Treatments: Drug: albendazole

Study type: Interventional

Funder types: Other

Identifiers

NCT01192802

Albendazole-001

Details and patient eligibility

About

Albendazole is a main anti-helminth, however there is a lack of data regarding its efficacy in the school children population. The aim of this study is to evaluate the efficacy of the albendazole one versus two and three doses, in school children infected with intestinal helminth.

Enrollment: 200 patients

Sex: All

Ages: 4 to 14 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• presence of intestinal helminths eggs in the stool

Exclusion criteria

• allergy to imidazole derivate
• No intestinal helminths

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Single Blind

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200 participants in 3 patient groups

1 dose, Albendazole , tablet

Active Comparator group

Treatment:

Drug: albendazole

Drug: albendazole

Drug: albendazole

2 doses, albendazole, tablet

Active Comparator group

Description:

1 tablet of 400 mg of albendazole per day for two consecutive days

Treatment:

Drug: albendazole

Drug: albendazole

Drug: albendazole

3 doses albendazole, 400mg, tablet

Active Comparator group

Treatment:

Drug: albendazole

Drug: albendazole

Drug: albendazole