Efficacy of Application of Myriad Matrix to Split Thickness Skin Graft Sites

The University of Alabama at Birmingham

Status: Withdrawn

Conditions: Skin Grafts

Treatments: Procedure: Matrix Dressing

Study type: Observational

Funder types: Other

Identifiers

NCT06647394

IRB-300013305

UAB (Other Grant/Funding Number)

Details and patient eligibility

About

To determine if application of Myriad Matrix to split thickness skin graft donor sites improves post-operative pain and appearance of the wound.

Full description

In the head and neck practice at UAB, split thickness skin grafts are a commonly used procedure for simple reconstruction. The standard dressing for donor sites is a strip of vaseline gauze which remains on the site the wound dries, and the gauze eventually falls off. Post operative pain and poor wound healing is a well established complication of the donor site, and various methods have been studied in an attempt to reduce these complications for patients in the post operative period. (1, 2, 3)

Myriad matrix is an engineered extracellular matrix (Ovine Forestomach Matrix) used for soft issue repair in complex wounds. This has been sporadically used by some of the faculty members at UAB for split thickness skin graft donor site dressings with anectodal improvement in pain and healing, though this has not yet been studied to our knowledge.

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients 18 and over who are undergoing a split thickness skin graft at UAB.

Exclusion criteria

• Patients who are not planned to undergo a split thickness skin graft or who are unable or do not plan to attend follow up appointments will not be included.