Efficacy of Arnica D1 Ointment After Upper Blepharoplasty (ARINE)

Wynand BWH Melenhorst, MD

Status: Completed

Conditions: Blepharoplasty; Upper Eyelid Blepharoplasty

Treatments: Drug: Placebo ointment; Drug: Arnica

Study type: Interventional

Funder types: Other

Identifiers

NCT01598909

ARINE Study

Details and patient eligibility

About

Arnica ointment is currently used in homeopathic preparations for strains and bruises. In the field of plastic surgery, some surgeons advise patients undergoing blepharoplasty to use Arnica in order to prevent postoperative ecchymosis, swelling and pain. Thus far, no decent study evaluated the efficacy of topical Arnica ointment in reducing ecchymosis or surgical outcome after upper blepharoplasty. We hypothesize that application of Arnica ointment postoperatively will reduce the development of ecchymosis and improve outcome.

Enrollment: 136 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients undergoing primary blepharoplasty

Exclusion criteria

• use of anticoagulants

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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136 participants in 3 patient groups, including a placebo group

Arnica ointment

Active Comparator group

Treatment:

Drug: Arnica

Placebo ointment

Placebo Comparator group

Treatment:

Drug: Placebo ointment

Control

No Intervention group