Efficacy of Balanced Nutrition Meal Replacement Along With a Caloric Restriction on Body Weight Control (nutrition)

Chung Shan Medical University

Status: Completed

Conditions: Nutrient; Excess; Obesity; Diet Modification

Treatments: Dietary Supplement: Meal replacement diet

Study type: Interventional

Funder types: Other

Identifiers

NCT03642925

CS15124

Details and patient eligibility

About

The present study was designed to evaluate the impact of a nutritionally balanced conventional meal replacement diet with caloric restriction (intervention for 8 weeks) in Taiwanese obese subjects. Various parameters like anthropometric (body weight, body fat, waist circumference), lipid profile (TC, LDL-c and TG), cardiovascular risk factors, glycemic and oxidative markers as well as renal and hepatic markers were evaluated.

Full description

The present study was designed to evaluate the impact of a nutritionally balanced conventional meal replacement diet (rich in soy/pea protein and soluble fibers) with caloric restriction in Taiwanese obese subjects. Obese subjects (BMI>27; n=50, male 23, female 27) were recruited and requested to replace two meals/day (breakfast and lunch or dinner) by balanced nutritional meal replacement diet (equal to 240 kcal) for 8 weeks with one regular meal and make sure the daily target calorie limit should be less than 1500 kcal/day for men and 1200 kcal/day for women.

Enrollment: 50 patients

Sex: All

Ages: 20 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy obese subject (BMI >27)
• Aged between 20 to 80 of both genders with a desire to lose weight.

Exclusion criteria

• Subjects with cancer
• Hyperglycemic (diabetic)
• Hypertension,
• Stroke
• Renal dysfunction
• Cardiac or hepatic dysfunctio
• allergic to the dairy product and eating disorders
• Pregnancy, nursing (lactating), chain smokers and heavy alcoholic subjects

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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50 participants in 1 patient group

Meal replacement diet

Experimental group

Description:

Obese subjects (BMI\>27; n=50, male 23, female 27) were requested to replace (intervention) two meals/day (breakfast and lunch or dinner) by balanced nutritional meal replacement diet (equal to 240 kcal) for 8 weeks

Treatment:

Dietary Supplement: Meal replacement diet