Efficacy of Chinese Herbal Medicine to Prevent and Treat COVID-19 Close Contacts (CHM COVID-19)

Hong Kong Baptist University

Status

Completed

Conditions

Healthy Participants

Treatments

Drug: Chinese herbal medicine is in the form of granules (9 g/sachet), which is comprised of ten medicinal herbs.

Study type

Interventional

Funder types

Other

Identifiers

NCT05269511

CHM COVID-19

Details and patient eligibility

About

This is a randomized, blank-controlled study in adults with household contact exposure to individuals with SARS-CoV-2 infection. All subjects in the study will be household contacts with close exposure to the first household member known to be newly infected with SARS-CoV-2. Subjects in each cohort will be randomly assigned to the Chinese herbal medicine treatment group or blank control group in a 4:1 ratio, followed by 1 week of the treatment period and 2 weeks of follow-up.

Enrollment

2,163 patients

Sex

All

Ages

16+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Household contact exposure to individuals with SARS-CoV-2 infection
Aged ≥18
General healthy or have a chronic, stable medical condition
Voluntarily signing a written informed consent form
Able to follow written and oral instructions in Chinese

Exclusion criteria

Moderate to severe symptomatic SARS-CoV-2 infection
An allergic history to Chinese herbal drugs or a known allergy to the ingredients of the study drug
Pregnancy, breastfeeding or plan to become pregnant within the study timeframe
Vulnerable adults (i.e., mentally or physically disabled to take care of himself/herself)
Any physical examination findings, and/or history of any illness, or concomitant medications that, in the opinion of the study investigator, might not be suitable to participate in the study