Efficacy of Conservative Treatments for Urinary Incontinence in Women

Mackay Medical College

Status: Enrolling

Conditions: Urinary Incontinence

Treatments: Procedure: BT + bPFMT; Procedure: bPFMT + iVES; Procedure: BT; Procedure: iVES; Procedure: bPFMT; Procedure: BT + iVES

Study type: Observational

Funder types: Other

Identifiers

NCT05977231

23MMHIS058e

Details and patient eligibility

About

To conduct a retrospective study to examine the effect of these conservative treatments to the symptoms and quality of life of patients with urinary incontinence. The investigators will use both subjective and objective assessment parameters, such as self-report symptoms, bladder diary, pad test and urodynamic study to access the improvement.

Full description

Urinary incontinence is a common problem among women. The main types include stress incontinence, urge incontinence, and overflow incontinence. Other underlying pathology, such as cancer or neurologic disease can also cause urinary incontinence. To limit the medical expenses and possible complications of surgical treatment, the current treatment guidelines recommend conservative treatment as the first choice. According to American Urological Association (AUA)/Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction (SUFU) guidelines, the first-line treatment for non-neurologic overactive bladder should be behavioral therapy, such as bladder training, water restriction, and pelvic floor muscle training, physiological feedback, pessary, etc. Bladder training aims to increase the time interval between voids, and to increase the bladder capacity by self-adjusted schedules. Pelvic floor muscle training strengthens the pelvic floor muscles to provide urethral support to prevent urine leakage and suppress urgency. There is strong evidence that pelvic floor muscle training is beneficial for stress urinary incontinence.

The second-line treatment is medication, including anticholinergic drugs and ß3 adrenoceptor-acting agents. Anticholinergic drugs can reduce bladder detrusor contraction, and ß3 adrenoceptor-acting agents can relax the detrusor and increase bladder capacity.

Enrollment: 60 estimated patients

Sex: Female

Ages: 20 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult female patient diagnosed with urinary incontinence through clinical assessment
• Diagnosed at Mackay Memorial Hospital and underwent non-surgical treatment and subsequent follow-up.

Exclusion criteria

• Choosing invasive or surgical treatment options (such as bladder botulinum toxin injection, urethral sling surgery).
• Unable to comply with regular follow-up for at least one year.
• Pregnant women
• Patients with a history of neuromuscular disorders.

Trial design

60 participants in 6 patient groups

Bladder training (BT)

Description:

Data obtained before and after the training.

Treatment:

Procedure: BT

biofeedback-assisted pelvic floor muscle training (bPFMT)

Description:

Data obtained before and after the training.

Treatment:

Procedure: bPFMT

intra-vaginal electric stimulation (iVES)

Description:

Data obtained before and after the training.

Treatment:

Procedure: iVES

BT+bPFMT

Description:

Data obtained before and after the training.

Treatment:

Procedure: BT + bPFMT

BT+iVES

Description:

Data obtained before and after the training.

Treatment:

Procedure: BT + iVES

bPFMT+iVES

Description:

Data obtained before and after the training.

Treatment:

Procedure: bPFMT + iVES