Efficacy of Dextrose Prolotherapy Compare With ESWT in the Treatment of Chronic Rotator Cuff Tendinopathy

Mahidol University

Status: Completed

Conditions: Chronic Rotator Cuff Tendinopathy

Treatments: Procedure: Prolotherapy; Device: Extracorporeal shock wave therapy (ESWT)

Study type: Interventional

Funder types: Other

Identifiers

NCT06700746

COA.No.MURA2023/839

Details and patient eligibility

About

To compare the efficacy of dextrose solution injection with ESWT for pain reduction in rotator cuff tendinopathy.

Additionally, secondary objective is to evaluate DASH and active range of motion of shoulder joint

Enrollment: 24 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Chronic shoulder pain for at least 3 months
• Unilateral affected side
• History of unsuccessful conservative treatment
• Age 18 years or older

Exclusion criteria

• Rotator cuff complete tear
• Local or generalized arthritis
• Previous shoulder surgery
• Previous history allergy to local anesthesia
• Pregnancy
• Current infectious or tumorous disease
• Dysfunction in the neck or thoracic region of both
• Coagulation disturbance

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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24 participants in 2 patient groups

Prolotherapy

Experimental group

Description:

Solution 3.6 mL of 25% dextrose and 0.4 mL xylocaine total 4.0 mL And Solution 3.5 mL of 15% dextrose and 0.8 mL xylocaine total 4.3 mL each site Injection interval week 0, 3 and 6 Ultrasound guided injection Injection into enthesis points

Treatment:

Procedure: Prolotherapy

Extracorporeal shock wave therapy (ESWT)

Active Comparator group

Description:

ESWT Treatment interval week 0, 1 and 2 Energy intensity 0.20-0.25 mJ/mm2 per impulse Frequency 4-5 Hz for 2,000 shocks

Treatment:

Device: Extracorporeal shock wave therapy (ESWT)