Efficacy of Dietary Education and Education on Phosphate Binder Use in Hemodialysis Patients

Ajou University School of Medicine

Status: Completed

Conditions: Hyperphosphatemia; End-stage Renal Disease

Treatments: Behavioral: Dietary education; Behavioral: Education on phosphate binder use

Study type: Interventional

Funder types: Other

Identifiers

NCT02755961

MED-SUR-15-147

Details and patient eligibility

About

Hyperphosphatemia is an independent risk factor for mortality among dialysis patients. And most phosphate in human is derived from the food. The purpose of this study is to evaluate the efficacy of nutritional consultation and education on phosphate binder among dialysis patients.

Full description

Hyperphosphatemia is an independent risk factor for mortality among dialysis patients. Hyperphosphatemia is associated with increased incidence of cardiovascular diseases, and is a mediator to the development of hyperparathyroidism and mineral bone disorder. Phosphate is usually obtained by food intake, and it can be removed by hemodialysis. However, the efficacy of removal is limited, so that dietary education and proper intake of phosphate binder is essential.

Enrollment: 70 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• End-stage renal disease patients whose dialysis vintage is more than 3 months

Exclusion criteria

• Patients with liver cirrhosis
• Pregnant patients
• Patients with alimentary tract malabsorption diseases
• History of recent alcohol or drug abuse
• Patients receiving chemotherapy for solid organ tumor
• History of mental illness (major depressive disorder, bipolar disorder, schizophrenia, etc.)
• Patients having difficulty communicating with our medical team (dementia, mental retardation, etc.)

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

70 participants in 2 patient groups

Control group

No Intervention group

Description:

No intervention was performed

Education group

Experimental group

Description:

Dietary education and education on phosphate binder use. Pharmacists instructed patients about how to take phosphate binders properly. Dietitians educated on dietary phosphate restriction.

Treatment:

Behavioral: Education on phosphate binder use

Behavioral: Dietary education