Efficacy of Different Nerve Stimulation Methods in Individuals With Chronic Constipation

Medipol Health Group

Status: Completed

Conditions: Constipation

Treatments: Device: Tibial Nerve Stimulation; Device: Auricular vagus stimulation

Study type: Interventional

Funder types: Other

Identifiers

NCT05833191

Chronic Constipation

Details and patient eligibility

About

Constipation is the most common digestive complaint in the general population. Normal stool frequency ranges from at least three times a week to a maximum of two times a day. Constipation can be classified into three main groups as constipation with normal transit time, constipation with slow transit time and dyssynergic defecation disorders.

Full description

In chronic constipation, treatment should be directed towards the underlying cause. In the treatment of chronic constipation, lifestyle changes and physiotherapy are in the first place, pharmacological treatment is in the second place, and surgical treatment is in the third place. Physiotherapy modalities such as defecation training, classical massage, electrical stimulation, anorectal biofeedback and exercise training can be used in the treatment of chronic constipation.

Enrollment: 16 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

•Being diagnosed with chronic constipation

Exclusion criteria

• Metabolic diseases
• Severe heart or kidney disease, previous gastrointestinal, spinal or pelvic surgery other than cholecystectomy, hysterectomy or appendectomy,
• Neurological diseases such as multiple sclerosis, stroke, Parkinson's disease or spinal injury, impaired awareness
• Mini-mental score < 15
• Legal blindness, pregnancy, rectal prolapse, anal fissure, and alternating pattern of constipation and diarrhea.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

16 participants in 2 patient groups

Auricular vagus stimulation

Experimental group

Description:

Non-invasive transcutaneous devices stimulate the vagus nerve via the auricular route or from the carotid.

Treatment:

Device: Auricular vagus stimulation

Tibial Nerve Stimulation

Experimental group

Description:

Transcutaneous tibial nerve stimulation (TTNS) is reported to be beneficial for fecal and urinary incontinence. A review of the literature showed that there are very few studies using TTNS that have been shown to be effective for constipation.

Treatment:

Device: Tibial Nerve Stimulation