Efficacy of Different Types of Chemical Peels in the Treatment of Acne Vulgaris (AV)

Nahla Maher Mahmoud Mahran

Status: Completed

Conditions: Peeling; Acne

Treatments: Procedure: salicylic acid; Procedure: Glycolic acid peel alone; Procedure: modified jessener

Study type: Interventional

Funder types: Other

Identifiers

NCT07240051

MS-327-2023

Details and patient eligibility

About

Assessment of the Efficacy and Safety of 50% Glycolic Acid, 30% Salicylic Acid, and Modified Jessner's Chemical Peels in the Treatment of Active Acne and Post-acne Hyperpigmentation: Randomized Controlled Trial.

Enrollment: 90 patients

Sex: All

Ages: Under 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Facial active acne (mild and moderate cases)
• post-acne hyperpigmentation
• a minimum age of 18 years
• skin phototype III or IV

Exclusion criteria

• Pregnant or nursing women
• active infection in the treatment area (e.g., verrucae and herpes simplex)
• systemic disease (hypertension, diabetes, or bleeding tendency)
• systemic retinoid or laser treatment within the last 6 months
• history of keloidal tendency or Aspirin sensitivity.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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90 participants in 3 patient groups

glycolic acid group

Active Comparator group

Description:

30 patients received 50% glycolic acid peels

Treatment:

Procedure: Glycolic acid peel alone

Salicylic acid group

Active Comparator group

Description:

30 patients received Salicylic acid 30%

Treatment:

Procedure: salicylic acid

Modified Jessener group

Active Comparator group

Description:

30 patients received MJ peel

Treatment:

Procedure: modified jessener