Efficacy of Endoscopic Band Ligation (DEBL) for Duodenal Neuroendocrine Neoplasms(dNENs)

Asian Institute of Gastroenterology, India

Status: Completed

Conditions: Duodenal Neuroendocrine Tumor

Treatments: Procedure: duodenal ndoscopic bind ligation

Study type: Observational

Funder types: Other

Identifiers

NCT06790056

DEBL- 01

Details and patient eligibility

About

Primary objective To evaluate the therapeutic efficacy (clinical success) of dEBL at 3 months

2b. Secondary objective

To evaluate adverse events, technical success and recurrence on follow-up

50 patients over 1-year duration based on our previous study of Prospective data (2023-2024)

Full description

We will collect your basic demographics details like age, Sex, date of admission, Endoscopy (is a test to look inside your body) details of Site, size, number of lesion.

By EUS (Endoscopic ultrasound (EUS) combines two techniques - endoscopy and ultrasound - to help doctors see, evaluate and diagnose conditions in and near the gastrointestinal (GI) tract) details of layer of Duodenum involved, site/size/number of lesions.

We will collect your details of Duodenal endoscopic band ligation procedure to check feasibility, technical success.

You are requested to come for follow up for 3 months for endoscopy prodecure.

Enrollment: 50 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients age >18 years
• Size of lesion less than 15mm
• Site of lesion- duodenum (d1-d4)
• No of lesions- ≤6

Exclusion criteria

• Age less than 18 years
• Non-duodenal lesion
• Local or distant metastasis
• Lumen occluding lesions
• Uncorrectable coagulopathy
• Not willing for consent

Trial design

50 participants in 1 patient group

Duodenal endoscopic band ligation group

Description:

We will collect your basic demographics details like age, Sex, date of admission, Endoscopy (is a test to look inside your body) details of Site, size, number of lesion. By EUS (Endoscopic ultrasound (EUS) combines two techniques - endoscopy and ultrasound - to help doctors see, evaluate and diagnose conditions in and near the gastrointestinal (GI) tract) details of layer of Duodenum involved, site/size/number of lesions. We will collect your details of Duodenal endoscopic band ligation procedure to check feasibility, technical success. You are requested to come for follow up for 3 months for endoscopy prodecure.

Treatment:

Procedure: duodenal ndoscopic bind ligation