Efficacy of Erector Spinae Plane Block Analgesia After Off Pump Cardiac Surgery (ESPB)

Menoufia University

Status: Completed

Conditions: Postoperative Pain

Treatments: Drug: Fentanyl; Procedure: Erector spinae block

Study type: Interventional

Funder types: Other

Identifiers

NCT05769309

2/2023 ANET10-2

Details and patient eligibility

About

In this study the investigators will investigate the efficacy of ESPB as a part of Enhanced recovery after surgery on postoperative analgesia and recovery criteria after off pump cardiac surgery.

Full description

General anaesthesia will be induced by 0.05 mg/kg midazolam, 3 µg/kg fentanyl, 1-2mg/kg propofol, and 0.5mg/kg of Atracurium. After induction, bilateral erector spinae plane block will be performed in the block group. Intraoperative analgesia will be achieved by fentanyl boluses of 0.5-to-1 µg/kg titrated according to haemodynamic parameters. Postoperative analgesia will be managed by paracetamol 1000 mg /6hours and morphine 1-2mg boluses when pain score ≥4 1 to 2 mg to be repeated every 5 minutes if needed.

Enrollment: 50 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age 18-70 years
• ejection fraction of > 45%
• undergoing elective off-pump cardiopulmonary bypass surgery

Exclusion criteria

• vertebral anomalies
• intra-aortic balloon pump in the preoperative period
• acute myocardial infarction
• local infection at the site of block
• allergy to the local anesthetic used
• morbid obesity, psychiatric disorders, neurologic deficits, alcohol and chronic opioid abuse, and patients with bleeding diathesis.

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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50 participants in 2 patient groups

Erector spinae block group

Active Comparator group

Description:

the patients will be administered bilateral Erector spinae block with 20 ml of 0.25 % bupivacaine

Treatment:

Drug: Fentanyl

Procedure: Erector spinae block

control group

Other group

Description:

no block will be done but only IV analgesia.

Treatment:

Drug: Fentanyl