Efficacy of External Nasal Nerve Block in Prevention of Postoperative Agitation Following Nasal Surgeries

Al Jedaani Hospital

Status: Completed

Conditions: Agitation States as Acute Reaction to Gross Stress

Treatments: Drug: Xylocaine, adrenaline; Drug: saline adrenaline; Procedure: External nasal nerve block

Study type: Interventional

Funder types: Other

Identifiers

NCT03069027

3-2-17

Details and patient eligibility

About

Emergence agitation following general anaesthesia may lead to serious complications like self-extubation or removal of catheters, which can lead to hypoxia, aspiration pneumonia, bleeding or reoperation. Nose surgery is associated with a higher incidence of emergence agitation. The investigators planned to evaluate the efficacy of external nasal nerve block in prevention of postoperative agitation following external nasal surgeries under general anesthesia(GA).

Enrollment: 100 patients

Sex: All

Ages: 20 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 110 adult patients of ASA physical status I and II,
• Age 20-60 years,
• Scheduled for elective external nasal surgeries in which nasal packing on each side was used postoperatively for 24 hours.

Exclusion criteria

1. History of uncontrolled hypertension,
2. Ischemic or valvular heart disease,
3. Use of MAO inhibitors or adrenergic blocking drugs,
4. Cognitive impairment,
5. Patients taking antipsychotics,
6. Renal insufficiency or liver dysfunction

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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100 participants in 2 patient groups, including a placebo group

Group I(control)

Placebo Comparator group

Description:

patients allocated for external nasal nerve block with saline adrenaline 1/200,000 (placebo)

Treatment:

Procedure: External nasal nerve block

Drug: saline adrenaline

Group II(block)

Active Comparator group

Description:

'External nasal nerve block by Xylocaine, adrenaline'

Treatment:

Drug: Xylocaine, adrenaline

Procedure: External nasal nerve block