Efficacy of Fascia Lata Allograft and Platelet Rich Fibrin on the Periodontal Phenotype Around Dental Implant

Kafrelsheikh University

Status and phase: Not yet enrolling; Phase 4

Conditions: Allograft

Treatments: Drug: Platlet Rich fibrin membrane; Drug: subepithelial connective tissue graft; Drug: Fascia lata membrane

Study type: Interventional

Funder types: Other

Identifiers

NCT06219473

KFSIRB200-87

Details and patient eligibility

About

To compare between the efficacy of fascia lata allograft and platelet rich fibrin versus subepithelial connective tissue graft on periodontal phenotype (thickness and width of keratinized tissue, labial bone thickness) around dental implant in upper anterior region.

Full description

In order to evaluate the effectiveness of fascia lata allograft, platelet-rich fibrin, and subepithelial connective tissue graft on periodontal phenotype (including the thickness and width of keratinized tissue, as well as the thickness of labial bone) around dental implants in the upper anterior region, the purpose of this study is to compare the three types of grafts.

Enrollment: 24 estimated patients

Sex: All

Ages: 20 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Patients with thin gingival biotype (gingival thickness was ≤1 mm)
2. The height of keratinized gingiva for the site selected should be ≥2 mm.
3. Ability to maintain good oral hygiene as evidenced in recall visits.

Exclusion criteria

1. Smoker patient and pregnant or lactating woman.
2. Patient with poor oral hygiene or active periodontal disease.
3. Traumatic occlusion or para-functional habits such as clenching or bruxism.
4. Patient with limited mouth opening

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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24 participants in 3 patient groups

Fascia Lata (Study group)

Experimental group

Description:

It includes eight patients seeking for implant placement in the upper anterior areas and implants will be placed with the application of fascia lata allograft membrane.

Treatment:

Drug: Fascia lata membrane

PRF (Study group)

Experimental group

Description:

It includes eight patients seeking for implant placement in the upper anterior area and implants will be placed with the application of PRF.

Treatment:

Drug: Platlet Rich fibrin membrane

Connective tissue Graft(Control group)

Active Comparator group

Description:

It includes eight patients seeking for single implant placement at the upper anterior area and those patients will be received their implants with subepithelial connective tissue graft.

Treatment:

Drug: subepithelial connective tissue graft