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Efficacy of Fluoride Varnish Containing Xylitol Coated Calcium Phosphate Versus Conventional Fluoride Varnish in Management of Hypersensitivity of Exposed Root Surfaces in Adult Patients

Cairo University (CU) logo

Cairo University (CU)

Status and phase

Completed
Phase 1

Conditions

Hypersensitivity

Treatments

Drug: Fluoride varnish with xylitol coated calcium and phosphate

Study type

Interventional

Funder types

Other

Identifiers

NCT04472182
CairoUniv

Details and patient eligibility

About

This clinical trial will be conducted to compare the efficacy of fluoride varnish containing xylitol coated calcium and phosphate or potassium nitrate gel versus conventional fluoride varnish in the management of hypersensitivity of non-carious exposed root surfaces in adult patients over a 12 months period.

Enrollment

105 patients

Sex

All

Ages

20 to 50 years old

Volunteers

Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria of participants:

Males or females. Age: 20-50 years old. Patients having at least one tooth with exposed root surface Teeth with hypersensitivity, VAS ≥5 Patients with good oral hygiene. Co-operative patients who show interest to participate in the study

Exclusion criteria of participants:

Patients with bad oral hygiene Patients with orthodontic appliances, or bridge work that might interfere with evaluation Patients who are allergic to any ingredients will be used in the study. Carious teeth Mobile teeth. (Grade 2 or Grade 3) Teeth with hypersensitivity, VAS <5 Patients with physical disabilities Pregnant or lactating women Other dental defects that causes pain. Allergy from any used materials or any allergic reaction during our clinical trial (The trial will be stopped at once and all the needed management against any allergic reaction will be done.)

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

105 participants in 2 patient groups

Fluoride varnish with xylitol coated calcium and phosphate
Experimental group
Treatment:
Drug: Fluoride varnish with xylitol coated calcium and phosphate
Conventional Fluoride varnish
Active Comparator group
Treatment:
Drug: Fluoride varnish with xylitol coated calcium and phosphate

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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