Efficacy of Genicular Block on Total Knee Arthroplasty Surgery

Mersin University

Status: Not yet enrolling

Conditions: Genicular Nerves Block; Total Knee Anthroplasty

Treatments: Drug: Patient Control Analgesia (PCA) Morphine group; Drug: Paracetamol (acetaminophen) + Diclofenac Sodium; Drug: Genicular blocks (bupivakain)

Study type: Interventional

Funder types: Other

Identifiers

NCT06942702

MersinUgenicular

Details and patient eligibility

About

The aim of this study is to investigate the postoperative pain relieving effect of preoperative genicular block in total knee arthroplasty surgery. The main questions it aims to answer are:

1. Do visual analog scale (VAS) scores decrease in patients who underwent geniculate block?
2. Does opioid consumption decrease in patients who underwent geniculate block?

Researchers will compare postoperative pain in patients who received genicular block with those who did not.One group of patients will be administered 0.25% bupivacaine with the geniculate block method. The other group will not undergo any intervention. Both groups will be administered intravenous morphine for postoperative analgesia.

Full description

Patients scheduled for knee arthroplasty will be randomly assigned into two groups. One group will receive a genicular nerve block prior to surgery without the administration of general anesthesia, while the other group will not undergo any interventional procedure. The genicular nerve block will be administered in three quadrants around the knee, with each injection consisting of 5 mL of 0.25% Marcaine. All injections will be performed by investigator MA. Patient assessments will be conducted by investigator MO. Postoperative intravenous analgesia will be provided to both groups.

Enrollment: 44 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Scheduled for unilateral and primary total knee arthroplasty
• Older than 18 years of age

Exclusion criteria

• Younger than 18 years
• Bilateral knee arthroplasty
• Revision case of knee arthroplasty

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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44 participants in 2 patient groups

Genicular block group

Active Comparator group

Description:

this group consists of the patients receiving genicular block preoperatively and they will be given morfin with PCA (Patient controlled analgesia) and paracetamol 3x1000 mg intravenous and diclofenac 75 mg intramuscular (if needed)

Treatment:

Drug: Genicular blocks (bupivakain)

Drug: Paracetamol (acetaminophen) + Diclofenac Sodium

Drug: Patient Control Analgesia (PCA) Morphine group

patients only given PCA-morfin postoperatively

Active Comparator group

Description:

this group consists of the patients given morfin with PCA, paracetamol 3x1000 mg and diclofenac (if needed)

Treatment:

Drug: Paracetamol (acetaminophen) + Diclofenac Sodium

Drug: Patient Control Analgesia (PCA) Morphine group