Efficacy of Hemostasis by Soft Coagulation Using Endoscopic Hemostatic Forceps for Acute Peptic Ulcer Bleeding

Kyung Hee University

Status: Completed

Conditions: Active Peptic Ulcer Disease/GI Bleeding

Treatments: Device: epinephrine injection plus soft coagulation using hemostatic forceps; Device: epinephrine injection plus argon plasma coagulation

Study type: Interventional

Funder types: Other

Identifiers

NCT02020603

GUB2013

Details and patient eligibility

About

Endoscopic high-frequency soft coagulation is available for the management of bleeding or nonbleeding visible vessels during endoscopic submucosal dissection. However, its efficacy on peptic ulcer bleeding has not been elucidated so far. The aim of this study was to evaluate the efficacy of hemostasis with soft coagulation using hemostatic forceps by comparing it with argon plasma coagulation (APC) in a prospective, randomized trial.

Enrollment: 151 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age greater than 18 years
• peptic ulcer with stigmata of recent hemorrhage

Exclusion criteria

• malignant ulcer
• previous gastric surgery

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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151 participants in 2 patient groups

APC group

Active Comparator group

Description:

epinephrine injection plus argon plasma coagulation

Treatment:

Device: epinephrine injection plus argon plasma coagulation

Forceps group

Active Comparator group

Description:

epinephrine injection plus soft coagulation using hemostatic forceps

Treatment:

Device: epinephrine injection plus soft coagulation using hemostatic forceps