Efficacy of i-PRF Usage in Vestibular Socket Therapy

Al-Azhar University

Status: Active, not recruiting

Conditions: Esthetic Zone

Treatments: Procedure: Immediate implant with VST and i-prf; Procedure: Immediate implant with VST

Study type: Interventional

Funder types: Other

Identifiers

NCT07304986

921/1704

Details and patient eligibility

About

This study aims for evaluation of A novel method for evaluating i-PRF usage in vestibular socket therapy for immediate implant in defective fresh extraction site.

Full description

The ultimate objective of implant treatment is providing long-lasting, healthy hard and soft tissue architecture while minimizing intraoperative surgical trauma and postoperative complications. Reducing treatment duration and providing a predictable esthetic outcome are fundamental. Immediate implant placement in fresh extraction sockets is an appealing treatment option satisfying many of these requirements. However, a major concern with immediate implant placement is the possible resorption of the facial bone plate as indicated in multiple studies. This, in turn, results in loss of proper soft tissue support, thus compromising the final esthetic outcome of the implant- supported restoration. Furthermore, post extraction bone resorption would be compounded by the presence of a thin or preexisting facial bone defect and/or a thin gingival phenotype. Multiple approaches were suggested to prevent facial bone resorption and optimize the final esthetic outcome after immediate implant placement in sockets with intact facial bone and soft tissue. These approaches include simple ones like applying a graft in the gap between the implant and the facial socket wall and more sophisticated approaches such as the socket shield technique . The presence of bone and/or soft tissue defects after tooth extraction is not an uncommon finding, further complicating immediate implant placement. Several classifications for fresh extraction sockets were proposed to facilitate the selection of optimum treatment for individual cases.

Currently, a serious of studies has shown that iPRF can produce significantly greater concentrations of platelets and leukocytes when compared to the L-PRF and A-PRF.

Enrollment: 24 patients

Sex: All

Ages: 15 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients has one hopeless tooth in the maxillary anterior region with TYPE II according to Elian classification of sockets (10) and sufficient bone apically and palatally.
• The presence of a natural contralateral tooth for the tooth being replaced.

Exclusion criteria

• Extraction sockets were grade III.
• Acute infection related to hopeless tooth.
• Allergy to any material or medication used in the study.
• Medically compromised patients according to modified Cornell Medical Index.
• Heavy smokers.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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24 participants in 2 patient groups

deficient facial plate of bone management VST only

Experimental group

Description:

Sockets with deficient facial plate of bone and intact soft tissue will receive VST only.

Treatment:

Procedure: Immediate implant with VST

deficient facial plate of bone management with VST and iPRF.

Active Comparator group

Description:

Sockets with deficient facial plate of bone and intact soft tissue will receive VST and iPRF.

Treatment:

Procedure: Immediate implant with VST and i-prf