Efficacy of Lavender Aromatherapy on Anxiety and Pain Reduction During Awake Otolaryngologic Procedures

Cedars-Sinai Medical Center

Status: Enrolling

Conditions: Rhinitis, Vasomotor; Inferior Turbinate Hypertrophy; Chronic Rhinosinusitis (CRS); Vocal Fold Immobility; Thyroid Nodules

Treatments: Other: Placebo Aromatherapy; Other: Lavender Aromatherapy

Study type: Interventional

Funder types: Other

Identifiers

NCT07299474

STUDY00004415

Details and patient eligibility

About

The purpose of this study is to evaluate the efficacy of lavender aromatherapy in adult patients undergoing awake otolaryngologic procedures in the outpatient clinic setting. The main questions it aims to answer are:

• Does lavender aromatherapy help reduce anxiety and/or pain, and improve patient comfort during awake otolaryngologic procedures in the clinic?
• Do patients subjectively find aromatherapy relaxing and/or beneficial during the procedure?

Researchers will compare lavender aromatherapy to placebo (an odorless liquid) to see if lavender aromatherapy helps improve patient comfort during their awake procedure

Participants will:

• Have their scheduled procedure performed with lavender aromatherapy or placebo during the duration of the procedure
• Take a short, less than 1 minute questionnaire both before and after the procedure, describing their levels of anxiety, pain and subjective impressions of the aromatherapy

Enrollment: 184 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adults ≥18 years old undergoing awake otolaryngologic procedures in the outpatient clinic
• Able to provide informed consent

Exclusion criteria

• Hypersensitivity to fragrances
• Taking systemic NSAIDs or other systemic pain-relieving medications within 48 hours
• Taking anxiolytics, hypnotics, sedating antihistamines, antidepressants on regular basis within 4 weeks
• Pregnant or breastfeeding
• Participation in another clinical research study within the prior 30 days

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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184 participants in 2 patient groups, including a placebo group

Lavender Aromatherapy

Experimental group

Description:

Participants will be exposed to lavender aromatherapy on a cotton ball prior to procedure, and then with a diffuser during the duration of the procedure

Treatment:

Other: Lavender Aromatherapy

Placebo

Placebo Comparator group

Description:

Participants will be exposed to placebo odorless liquid, on a cotton ball prior to procedure, and then with a diffuser during the duration of the procedure

Treatment:

Other: Placebo Aromatherapy