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Efficacy of Low Dose of Proton Pump Inhibitor in Treatment Bleeding Ulcers

D

Damascus Hospital

Status

Completed

Conditions

Peptic Ulcer Hemorrhage
Marginal Ulcer
Gastroduodenal Ulcer

Treatments

Drug: Omeprazole 40 MG

Study type

Observational

Funder types

Other

Identifiers

Details and patient eligibility

About

Determining the efficacy of low dose of PPI in management acute peptic ulcer bleeding

Full description

Determining the efficacy of low dose meaning 40 mg of omeprazole twice in management acute peptic ulcer bleeding

Enrollment

295 patients

Sex

All

Ages

18 to 90 years old

Volunteers

No Healthy Volunteers

Inclusion and exclusion criteria

Criteria:

Inclusion Criteria:

High risk ulcers defined according to the Forrest classification With respect to high-risk stigmata, active bleeding was defined as a continuous blood spurting (Forrest IA) oozing (Forrest IB) from the ulcer base. A non-bleeding visible vessel at endoscopy was defined as a discrete protuberance at the ulcer base(Forrest IIA).

An adherent clot was one that was resistant to forceful irrigation or suction (Forrest IIB).

Exclusion Criteria:

ulcer was malignant non ulcerative bleeding such as angiodysplasia , a Mallory-Weiss tear

Trial design

295 participants in 1 patient group

Low Dose PPI
Description:
patients with upper upper gastrointestinal bleeding were treated in low dose of proton Bump inhibitor meaning 40 mg twice daily
Treatment:
Drug: Omeprazole 40 MG

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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