Efficacy of Lyophilized Dried Cornus Mas L. on Anthropometric and Biochemical Parameters in Insulin Resistance

Marmara University

Status: Completed

Conditions: Insulin Resistance; Obesity; PreDiabetes

Treatments: Behavioral: Diet; Dietary Supplement: Cornelian Cherry (Cornus mas L.)

Study type: Interventional

Funder types: Other

Identifiers

NCT05292300

09.2018.652

Details and patient eligibility

About

The aim of this study is to determine the effect of 3 months supplementation of lyophilize dried cornelian cherry (Cornus mas L.) on women diagnosed with insulin resistance. The baseline and end biochemical parameters and anthropometric measurements will be compared with control subjects.

Full description

The main purpose of this study is to determine the efficacy of the lyophilizer-dried powder form of cornelian cherry (Cornus mas L.) grown in our country on inflammation in women with insulin resistance by biochemical parameters.

Sub-objectives of the study;

• Determining the presence of inflammation in women with insulin resistance.
• Determination of the effect of cornelian cherry on both fasting blood glucose, insulin and blood lipid profile.
• Determination of both anti-inflammatory, antidiabetic and antioxidant effects of cornelian cherry.
• Determination of the effect of cornelian cherry on anthropometric measurements.

The aim of this study is to compare the anthropometric measurements and biomarkers of women with insulin resistance as a result of the consumption of powdered cornelian cherry (Cornus mas L.) that has been freeze-dried at -55 degrees with a Lyophilizer device for 12 weeks.

Enrollment: 84 patients

Sex: Female

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Women aged between 18 and 45 years with insulin resistance.
• Those who have not experienced menopause
• Those who applied to the obesity clinic
• Volunteers
• Those who signed the consent form

Exclusion criteria

• Those who use medicine for diabetes and thyroid diseases,
• Those taking hormone therapy
• Pregnant and lactating women
• Those with a history of cancer
• Patients with communication problems.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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84 participants in 4 patient groups

Control Group

No Intervention group

Description:

Among those who applied to the clinic, those who do not want to follow their diet will be randomized into this group.

Cornelian Cherry Group

Experimental group

Description:

Among those who applied to the clinic, those who do not want to follow their diet will be randomized into this group. Patients in this group will receive 20 g/day Cornelian Cherry powder.

Treatment:

Dietary Supplement: Cornelian Cherry (Cornus mas L.)

Diet Group

Experimental group

Description:

Among those who applied to the clinic, those who want to follow their diet will be randomized into this group. Patients in this group will be followed by a personalized diet.

Treatment:

Behavioral: Diet

Cornelian Cherry and Diet Group

Experimental group

Description:

Among those who applied to the clinic, those who want to follow their diet will be randomized into this group. Patients in this group will be followed by a personalized diet and will receive 20 g/day Cornelian Cherry powder for their one portion fruit a day.

Treatment:

Dietary Supplement: Cornelian Cherry (Cornus mas L.)

Behavioral: Diet