Efficacy of Lyophilized Food Extracts for Skin Prick Tests and Atopy Patch Test at Different Storage Time

Mahidol University

Status: Completed

Conditions: Food Allergy

Treatments: Diagnostic Test: skin test with food at different storage times

Study type: Interventional

Funder types: Other

Identifiers

NCT03645629

619/2556 (EC 3)

Details and patient eligibility

About

Comparison the result of skin prick tests and atopy patch test of lyophilized food extracts at different storage time (0, 3 and 6 months) after preparation

Full description

Skin prick test were performed with lyophilized food extracts (cow milk, egg white, egg yolk, wheat, soy and shrimp) at different storage time (0, 3 and 6 months) after preparation.

Atopy patch test were performed with lyophilized food extracts (cow milk, egg white, egg yolk, wheat, soy and shrimp) at different storage time (0, 3 and 6 months) after preparation

Enrollment: 40 patients

Sex: All

Ages: 3 to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• mild to moderately severe food allergy patients
• At least positive skin test to one kind of common food (commercial extract)
• Stop antihistamine or corticosteroid (if more than 20mg/day) for at least 7 days

Exclusion criteria

• Dermographism
• Severe systemic disease such as autoimmune disease, immune deficiency, malignancy
• Severe dermatitis or large area involment
• pregnancy

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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40 participants in 3 patient groups

Food skin tests at 0 month

Active Comparator group

Description:

the skin test results of food extract at time 0 months after preparation

Treatment:

Diagnostic Test: skin test with food at different storage times

Food skin tests at 3 month

Active Comparator group

Description:

the skin test results of food extract at time 3 months after preparation

Treatment:

Diagnostic Test: skin test with food at different storage times

Food skin tests at 6 month

Active Comparator group

Description:

the skin test results of food extract at time 6 months after preparation

Treatment:

Diagnostic Test: skin test with food at different storage times