Efficacy of Median Nerve Hydrodissection by Hyalase Versus Midazolam in the Treatment of Carpal Tunnel Syndrome:

Minia University

Status and phase: Enrolling; Early Phase 1

Conditions: Pain, Neuropathic

Treatments: Drug: hyalase group; Drug: midazolam group

Study type: Interventional

Funder types: Other

Identifiers

NCT05344495

277/4-2022

Details and patient eligibility

About

Comparing efficacy of hyalase and midazolam in median nerve entrapement neuropathy

Enrollment: 100 estimated patients

Sex: All

Ages: 30 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• adult patients (30 - 70 years old) complaining of carpal tunnel syndrome of 3 month duration or more , diagnosed axonal neuropathy using electrodiagnosis , nerve conduction study refractory to medical treatment for 2 months .

Exclusion criteria

• Diabetic patients
• Pregnant population .
• Refusal to participate

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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100 participants in 2 patient groups

hyalse group

Active Comparator group

Description:

ultrasonographic median nerve hydrodissection by hyalase and bupivacaine 0.5%

Treatment:

Drug: hyalase group

midazolam group

Active Comparator group

Description:

ultrasonographic median nerve hydrodissection by midazolam and bupivacaine 0.5%

Treatment:

Drug: midazolam group