Efficacy of Metformin in Lean Women With Polycystic Ovary Syndrome

Aarhus University Hospital Skejby

Status: Unknown

Conditions: Polycystic Ovary Syndrome

Treatments: Drug: Metformin

Study type: Interventional

Funder types: Other

Identifiers

NCT00319293

160350-2

Details and patient eligibility

About

Insulin resistance is an important feature of the polycystic ovary syndrome,and patiens are successfully treated with the insulin sensitizing agent metformin. The insulin resistance of lean patients with the syndrome is debated. In this study, we will study the change in insulin resistance, metabolic and hormonal factors after 3 months of metformin treatment in lean PCOS women.

Sex: Female

Ages: 20 to 35 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• PCOS (Rotterdam criteria)
• BMI < 27
• No medication for 3 months

Exclusion criteria

• Pregnancy
• Lactation
• Other endocrinologic disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind