Efficacy of Methylsulfonylmethane Supplementation on Osteoarthritis of The Knee: A Randomized Controlled Study

Shamir Medical Center (Assaf-Harofeh)

Status: Completed

Conditions: Knee Osteoarthritis

Treatments: Dietary Supplement: Methylsulfonylmethane (MSM)

Study type: Interventional

Funder types: Other

Identifiers

NCT01188213

13/05

Details and patient eligibility

About

The aim of this study was to determine the efficacy of methylsulfonylmethane (MSM) in treating patients with knee OA.

Sex: All

Ages: 40 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• symptomatic knee OA for at least 6 months according to the clinical criteria of the American College of Rheumatology (ACR)
• radiographic confirmed knee OA according to the Kellgren & Lawrence scale

Exclusion criteria

• acute septic arthritis
• inflammatory arthritis
• any other type of arthritis
• history of knee buckling or recent knee injury
• lack of physical or mental bility to perform or comply with the treatment procedure
• diabetes mellitus
• fibromyalgia or other chronic pain syndromes
• concurrent anti-coagulant/anti-platelet drugs
• arthroscopy or intra-articular injections in the previous 3 months

Trial design

0 participants in 1 patient group

Purified MSM

Experimental group

Treatment:

Dietary Supplement: Methylsulfonylmethane (MSM)