Efficacy of Novel Edible Gel-based Artificial Saliva in Cancer Patients

Dental Innovation Foundation Under Royal Patronage

Status: Completed

Conditions: Cancer of Head and Neck; Radiation-induced Xerostomia; Cancer; Dry Mouth

Treatments: Other: Gel-based artificial saliva

Study type: Interventional

Funder types: Other

Identifiers

NCT01885065

DIF-02

Details and patient eligibility

About

The purpose of this study is to determine whether continuous use of edible, gel-based artificial saliva in cancer patients with dry mouth problems will reduce signs and symptoms of dry mouth and improve quality of patients' saliva.

Enrollment: 25 patients

Sex: All

Ages: 35 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• cancer patients who receive/ had received radiotherapy and/or chemotherapy and have dry mouth problems

Exclusion criteria

• mucositis more than grade 1
• cannot perform oral intake of gel-based artificial saliva eg. aspirate

Trial design

Primary purpose: Supportive Care

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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25 participants in 1 patient group

Gel-based artificial saliva

Experimental group

Description:

Continuous oral intake of edible gel-based artificial saliva (30-50 ml/day) for four weeks

Treatment:

Other: Gel-based artificial saliva